Some US colleges change plans after infections among students

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(CNN)Colleges across the country are quickly learning it may be next to impossible to create a coronavirus-free environment on campus.

Young people helped drive a nationwide surge of new coronavirus cases over the summer and are now returning to college campuses across the country, seeding new outbreaks.

Despite efforts to keep the virus at bay, outbreaks have been traced to off-campus gatherings, sororities, fraternities and dorms, leaving schools to reassess how to proceed with the fall semester.

At Appalachian State University, in North Carolina, a cluster was associated with the football team. Iowa State University said 175 students tested positive for the virus -- about 2.2% of those tested -- during move-in.

"It's just extremely difficult to consider yourself to be in a bubble when there is a very high level of community spread around you or when people are coming from all over the country and congregating on college campuses," said Dr. Leana Wen, the former Baltimore City Health Commissioner. "You can't keep coronavirus out."

Across the US, the spread of the virus remains out of control. The 7-day average of daily new coronavirus cases in the US declined on Monday to 49,000, the first time it's been below 50,000 since July 6. Worldwide, that average daily total is surpassed only by India, which has four times the number of people.

Adjusted for population, Georgia, Texas and Florida have seen the most cases per day on average. All three states are led by governors who pushed to reopen during the spring, saw major summer surges of cases and are currently pushing to reopen schools. Texas has issued a mandate requiring face masks, but Georgia and Florida have not.

A man with possible Covid-19 symptoms is taken to the hospital on August 7 in Austin, Texas.

The US's 7-day average of new deaths has been over 1,000 per day for the past 23 days. In Florida, officials reported deaths of more than 200 people in a day Tuesday -- for at least the 10th time in the past month. More than 5.4 million Americans have been infected since the start of the pandemic and at least 171,821 have died.

While older Americans and those with underlying conditions are at greater risk of severe illness, health officials have emphasized it's not only those populations that should be cautious.

Coronavirus cases in children steadily increased from March to July, experts said earlier this month, and one in three children who were hospitalized were admitted to intensive care -- the same as adults.

And younger people who may recover from the virus with minimal symptoms and in many cases don't require hospitalization, still can have "residual symptoms for weeks and sometimes month," said Dr. Anthony Fauci, the director of the National Institute of Allergy and Infectious Diseases.

"We'd better be careful when we say 'Young people who don't wind up in the hospital are fine, let them get infected, it's OK.' No, it's not OK," Fauci said during an American Society for Microbiology briefing on Monday.

Universities rethinking amid outbreaks

About a dozen colleges have already reported cases of coronavirus on campus, and others are taking a more careful approach to reopening.

All undergraduate classes at the University of Notre Dame will be remote for the next two weeks after 147 students tested positive for coronavirus, the president announced this week.

UNC-Chapel Hill reported that 130 students had tested positive for coronavirus in the first week since classes began. The university is moving to remote learning for undergraduates starting Wednesday, school officials said in a letter about a week after classes started. The school said it still plans to play sports this fall, despite no longer holding in-person classes.

Hundreds of Covid-19 cases reported as students return to college campuses

University of Kentucky said 160 people have tested positive since school began on August 3. A significant number of parties, which violated the school's student code, has led to the rise in cases, according to the university's director of executive communication, Sarah Geegan.

At Colorado College, all 155 students in one dorm have been forced to quarantine after the college learned of a student who tested positive and did not practice proper social distancing guidelines.

At Drake University, 14 students were asked to leave the campus for two weeks after violating an agreement signed by students that outlined health and safety protocols for the year.

North Carolina State University, Iowa State University, Oklahoma State University, Northeast Mississippi Community College, Western Kentucky University and East Carolina University have all reported significant numbers of cases as well.

Others schools have seen the writing on the wall and adjusted their plans.

Ithaca College, in New York, which previously pushed back its fall in-person semester to October, announced this week it was shifting to remote instruction for the entire semester.

Michigan State University classes will begin remotely for all undergraduates, President Samuel L. Stanley announced.

FDA emergency authorization of blood plasma on hold

A US Food and Drug Administration emergency use authorization for blood plasma to treat Covid-19 is on hold, but could still be issued in the near future, Dr. H. Clifford Lane, deputy director at the National Institute of Allergy and Infectious Diseases, told The New York Times.

Scarce coronavirus vaccine should go to frontline health workers first, report suggests

The hold came after a group of federal health officials -- including National Institutes of Health Director Dr. Francis Collins, National Institute of Allergy and Infectious Diseases Director Dr. Anthony Fauci and Lane -- stepped in to argue the emerging data on the treatment was too weak, the Times reported Wednesday, citing two senior administration sources.

"The three of us are pretty aligned on the importance of robust data through randomized control trials, and that a pandemic does not change that," Lane told the Times.

Meanwhile, SalivaDirect, the test that got the green light from the FDA last week, could be in use by approved labs within the next few weeks, says Anne Wyllie, an epidemiologist at Yale School of Public Health who was part of the team responsible for the protocol.

"It's been actually very inspiring to see how many labs have already reached out to us -- how many are ready and willing to get going with SalivaDirect," Wyllie told CNN.

This is great news for many Americans who still have to wait several days to receive their results -- a waiting period that some health officials have called counterproductive to the country's efforts to get the virus under control.

The test doesn't require specialized supplies and can deliver results in less than three hours. Officials have called the test a "game changer" and one expert has also pointed to its expected low cost.

"We simplified the test so that it only costs a couple of dollars for reagents, and we expect that labs will only charge about $10 per sample," said Nathan Grubaugh, a Yale assistant professor of epidemiology.

CNN's Amanda Watts, Naomi Thomas, Annie Grayer, Jamiel Lynch, Giovanna Van Leeuwen and Jennifer Henderson contributed to this report.

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