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Scotland has recorded 486 new positive cases of coronavirus - the highest daily total since the outbreak began.
First Minister Nicola Sturgeon said the figures were concerning, and underlined why new restrictions had been imposed.
But she said it was important to remember that many more people are being tested now than at the peak of the outbreak earlier in the year.
Ms Sturgeon said 224 of the new cases were in Greater Glasgow and Clyde, with 107 in Lanarkshire and 57 in Lothian.
It brings the total number of positive cases in Scotland to 25,495, with Ms Sturgeon saying the number of cases in the Greater Glasgow and Clyde area included a "significant" outbreak at Glasgow University.
People across Scotland have been banned from visiting other people's homes from today, with Ms Sturgeon warning that the virus risks "spiralling out of control" unless urgent action was taken.
Speaking at her daily briefing on Wednesday, the first minister said: "The total number of positive cases reported yesterday was 486 - that is the highest number of positive cases we have ever recorded in a single day.
"It must be remembered that many more people are being tested now than was the case in the spring.
"Nevertheless, today's number represents 7.8% of people newly tested. That is obviously a real cause concern, but it also underlines why we took very decisive and very tough action yesterday."
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