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Israel is to impose a new national lockdown - becoming the first country in the world to take such a measure to contain the spread of coronavirus.
It will begin on Friday and last three weeks, including Jewish new year.
Prime Minister Benjamin Netanyahu said the measures would "exact a heavy price on us all", but the country faced a surge with 4,000 new daily infections.
A minister has resigned to protest against the restrictions that overlap with important Jewish festivals.
Housing Minister Yaakov Litzman, who leads an ultra-Orthodox Jewish party, said the measures would prevent Jewish people from celebrating their religious festivals, including Yom Kippur, the holiest day of the Jewish calendar, on 27 September.
He also threatened to pull his party out of the governing coalition.
What are the new restrictions?
Israel, which has a population of about nine million, has reported more than 3,000 new cases a day in recent weeks.
In a televised address on Sunday, the prime minister said this had grown to 4,000 daily.
The measures he announced will be the most extensive imposed in Israel since the first lockdown, which ran from late March until early May, and include:
Mr Netanyahu acknowledged the disruption the lockdown would cause to Jewish communities celebrating religious holidays that normally see families come together.
"This is not the kind of holiday we are used to. And we certainly won't be able to celebrate with our extended families," he said.
The restrictions on indoor gatherings will severely impact prayers in synagogues.
What did Yaakov Litzman say?
Mr Litzman said in his resignation letter on Friday: "This wrongs and scorns hundreds of thousands of citizens.
"Where were you until now? Why have the Jewish holidays become a convenient address for tackling the coronavirus?"
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image captionYaakov Litzman said the lockdown would prevent Orthodox Jews from being able to celebrate religious festivalsInterior Minister Aryeh Deri - who leads another ultra-Orthodox party - said in a video posted on Twitter that he supported the planned restrictions, and that not abiding by them would be tantamount to murder.
Addressing the cabinet as it convened to vote on the lockdown on Sunday, Mr Netanyahu said he regretted Mr Litzman's resignation.
He added: "We have to move on, to make the decisions necessary for Israel in the coronavirus era, and that is what we will do in this session."
Mr Netanyahu has faced criticism for his handling of the outbreak. Critics say his failure to tackle the virus effectively has led to another national lockdown.
Many nations are experiencing second surges of the virus. However most governments are now imposing smaller local lockdowns in affected areas, rather than blanket national ones.