People in Wales must wear face masks in shops and other indoor public spaces from Monday, the first minister has announced.
Mark Drakeford said the change came as 20 people in every 100,000 in Wales now had coronavirus.
Indoor meetings of more than six from an extended household will be illegal from Monday.
The rule will not apply to children under 11 and up to 30 people from different homes can still meet outside.
Mr Drakeford said the rate of 20 people in 100,000 was the "threshold we use for people to have to quarantine coming back into the UK".
He said if the figure fell, the advice on face masks could be looked at again.
The new mask rule was coming in from Monday to give people time to buy them and Mr Drakeford said he was "confident" people would follow the new rules.
Masks were not "some sort of magic wand" but "a sensible addition to the precautionary measures we are taking" to avert a crisis.
He added: "There will be signage, there will be policing, but policing is the last resort. What we want to do is educate, inform, persuade."
"We are introducing them now when in many parts of Wales the virus remains in low suppression.
"But because we are detecting a rise, particularly in some parts of Wales, we want to try and take measures to get ahead of this curve and try to stop it rising it the way that we have seen elsewhere, so we do not have to take even more significant measure in future."
Masks would not be mandatory in workplaces, Mr Drakeford said, and wearing them in school did "not seem proportionate."
He warned action could be taken if the six people rule was flouted.
Plaid Cymru leader Adam Price said the face coverings announcement "was very welcome" though the evidence on them was "never going to be 100%."
He said advice about how and when to use them needed to be "clear".
"We are at a critical point and we have to get a clear strong message out," he said.
Neil Butler, of teachers union NASUWT, worried about schools: "What amazes me about the first minister's statement this morning in terms of mandatory face coverings, in school classrooms where you've got these young adults crowded into classrooms, it's the opposite.
"The Welsh Government is positively saying no, we do not want face coverings in those particular environments."
Image copyright Getty Images Image caption Up to 30 people can meet outside in Wales from different householdsMinisters said restrictions on people meeting followed an increase in cases linked to people socialising indoors.
Up to four households have been able to form an extended household and meet since late August.
Until now, there has been no legal limit on how many people could gather.
Mr Drakeford said the rule of up to 30 people being allowed to meet outdoors would include peoples' gardens.
The new restriction will apply in pubs and restaurants, as well as private homes.
It comes after people in Merthyr Tydfil and Rhondda Cynon Taff were asked to wear masks in indoor public spaces and in work, and only use public transport if it was essential.
The new rules will not apply in Caerphilly county borough, which was put under local lockdown on Tuesday, where all extended household meetings are currently banned indoors.
Mr Drakeford will confirm the changes as part of his review into Wales' coronavirus restrictions at a press conference on Friday.
The move comes after other parts of the UK also restricted meetings to six - but did so both indoors and outdoors.
The UK government is restricting gatherings in England to just six people from Monday, with some exceptions.
The number of people that can meet in Scotland has also been cut to six.
Image copyright Getty Images Image caption Mark Drakeford will give a press conference on Friday on his latest reviewWales' coronavirus rules mean people can only be part of a single extended household, which cannot be changed once arranged.
Despite the gradual easing of restrictions over the summer, meetings indoors with anyone outside your extended household have remained illegal.
The recent rise in cases seen in Caerphilly county was blamed on people socialising in other people's homes in large numbers.
The area has seen one of the highest rates of cases in the whole of the UK, with 91.1 cases per 100,000 people over seven days.
On Thursday, residents of Rhondda Cynon Taff and Merthyr Tydfil were asked to follow a range of measures to avoid a local lockdown.
People have been asked to work from home if they can, not to visit care homes, and wear face masks in indoor or crowded public spaces.
Merthyr Tydfil has the second highest coronavirus case rate in Wales, after Caerphilly.