A preliminary Covid-19 vaccine trial involving 1,077 people in five UK hospitals suggests that it is safe

4 years ago 247
9 min ago

University of Oxford vaccine is safe and induces early immune reaction, early results suggest

From CNN Heath’s Jamie Gumbrecht

Preliminary results of a Phase 1/2 trial of a coronavirus vaccine developed by the University of Oxford suggest that it is safe and induces an immune response.

The vaccine provoked an antibody response within 28 days and a T-cell response within 14 days, according to a release from the medical journal The Lancet. 

The trial included 1,077 people age 18 to 55 with no history of Covid-19 and took place in five UK hospitals from late April to late May. Participants received the Covid-19 vaccine or the meningococcal conjugate vaccine, as a control group.

“The immune system has two ways of finding and attacking pathogens – antibody and T cell responses. This vaccine is intended to induce both, so it can attack the virus when it’s circulating in the body, as well as attacking infected cells,” University of Oxford Professor Andrew Pollard, the study’s lead author, said in a statement. “We hope this means the immune system will remember the virus, so that our vaccine will protect people for an extended period."

“However, we need more research before we can confirm the vaccine effectively protects against SARS-CoV-2 infection, and for how long any protection lasts,” the statement added.

There were no serious adverse event related to the vaccine; fatigue and headache were the most commonly reported reactions. Other common side effects included pain at the injection site, muscle ache, malaise, chills, feeling feverish and high temperature.

The vaccine is one of 23 Covid-19 vaccines currently in clinical trials globally, according to the World Health Organization.

10 min ago

The New York governor is traveling to Georgia to help with coronavirus response

From CNN's Kristina Sgueglia

New York Gov. Andrew Cuomo is heading to Savannah, Georgia, today, he said speaking from John F Kennedy International airport. 

He will meet with the mayor and his team to share what New York did, help them with testing and tracing programs, and will transport thousands of items of personal protective equipment.

"Whatever they need from us they’re going to get," Cuomo said.

He said when New York was “in the thick” of it, 30,000 health professionals from around the country offered to come to the state.  He said he was honored and touched by the generosity and said New Yorkers “don’t forget.”

“We’re doing everything we can now to pay it back," Cuomo added.

Per the law, Gov. Cuomo will not have to quarantine upon his return because he is an essential worker, he said.

Georgia is among the states where an incoming individual is required to quarantine upon arrival to New York for 14 days, per state mandate.

Cuomo said he will take a test upon his return.

Secretary to the governor Melissa De Rosa added the law also has an exception if you are passing through a state for less than 24 hours.

18 min ago

New York governor threatens to rollback reopening if people don't follow the rules

From CNN's Kristina Sgueglia

New York Gov. Andrew Cuomo issued a warning to revelers appearing to congregate in spite of the state mandates: “Don’t be stupid.”

He also threatened to roll back the opening plan if this continues. 

“We have to protect the progress we have made,” he said. “We are not in a static environment, a lot is going on.”

He said one main threat to New York’s progress is the number of congregations, primarily in downstate, and primarily involving young people. 

He said this with a slide showing images from Astoria, Queens, and the Lower East Side of Manhattan. “It has continued unabated and it is getting worse,” he said.

“I’m telling you in plain New York speak, as a born and bred New Yorker, it’s stupid what you’re doing… Don’t be stupid.” 

“We cannot allow those congregations to continue,” Cuomo said, adding, “if it happens.. we’re going to have to roll back the opening plan, and we’re going to have to close bars and restaurants.” 

He also called on local governments to enforce the law, not naming any governments in particular.

18 min ago

New York City enters phase 4 of reopening today — but it's not the same as the rest of the state

New York City is entering phase four of reopening today, but it's a slightly different phase four than other parts of New York state experienced.

Mayor Bill de Blasio announced last week that indoor dining would not be allowed to resume in phase four since it's considered a "high risk" activity.

In other parts of the state, indoor dining was allowed to resume in phase three.

De Blasio also announced that museums will also be “still closed for now." But shopping malls are included in phase four for areas of the state outside of New York City, according to state guidelines.

So here's a look at what will open in New York City's phase four, according to the mayor:

Low-risk outdoor entertainment activities, including things like botanical gardens and zoos, can reopen at a reduced capacity of 33%. Production of movies and TV shows can proceed.Sports can come back but without audiences.
19 min ago

At least 10 ICUs in Florida's Miami-Dade are at capacity

At least 10 adult ICUs in Miami-Dade County, the epicenter of Florida's coronavirus pandemic, have no beds available, according to Florida's Agency for Health Care Administration website as of 9 a.m. ET today.

For context, there are at least 24 hospitals in Miami Dade County with adult ICU bed capabilities. Ten of them — more than 40% — are at capacity. 

Nearby Broward County has at least six ICUs with 0% of bed available, according to the website.

You can check the ICU capacity at hospitals across Florida here.

29 min ago

These two Atlanta colleges will shift to digital learning this fall, students will not return to campus

From CNN's Tina Burnside

Morehouse and Spelman College in Atlanta, Georgia, announced on Monday that students will not be returning to campus for the Fall 2020 semester due to the recent spike in Covid-19 cases. 

"Because of the worsening health crisis, we have reluctantly come to the realization that we can no longer safely sustain a residential campus and in-person instruction. With a sense of great disappointment, I now share with you our decision that all instruction for the fall of 2020 at Spelman will be virtual," Spelman President Mary Schmidt Campbell said in a statement.

Both colleges had fully anticipated that they would open campuses for in-person instruction for the fall semester however due to the worsening health crisis in both the city of Atlanta and Fulton County, the colleges changed course, according to a news release. 

It remains unclear if the schools will reopen their campuses for students for the Spring 2021 semester. 

39 min ago

 Iraq nears 100,000 Covid-19 cases

From CNN’s Hamdi Alkhshali and Aqeel Najim

Iraq on Monday recorded 2,163 new coronavirus cases, according to the country's health ministry.

This brings the total number of Covid-19 cases in Iraq to 94,693 according to the ministry.

The health ministry also reported 88 new Covid-19-related deaths, bringing the total to 3,869 deaths across the country.

40 min ago

Bankers association urges America's banks to adopt mask policy

From CNN’s Cristina Alesci

The American Bankers Association (ABA), which represents large and small banks, joined other business groups in calling for its members to adopt national mask mandates “to protect the health of bank employees and customers.”  

"We owe it to frontline bank staff to prioritize their safety and to contribute to the wider effort to limit the spread of this infection," said Rob Nichols, ABA president and CEO, in a release on Monday.

Last week, The National Retail Federation urged all retailers to adopt a nationwide masks policies for customers. 

Other groups, including the Business Roundtable and the US Chamber of Commerce, lobbied President Trump and governors to enact a “national mask standard, implemented locally.”  

CNN’s Matt Egan contributed to this report

34 min ago

Getting retested for Covid-19 multiple times is completely unnecessary, US health official says

From CNN Health’s Naomi Thomas

US Assistant Secretary for Health and Human Services Admiral Brett Giroir told CNN’s Alisyn Camerota that getting retested multiple times for Covid-19 is unnecessary, if someone has been symptom-free for three or more days, or if it has been 10 or more days since the onset of their symptoms.

“It has always been a CDC guideline,” Giroir said on New Day Monday, “that if you are 10 days or more since the onset of your symptoms and you’re three days or more symptom free, you do not need to be retested.”

“We have lots of data now that shows after eight or nine days, you cannot transmit the virus – the virus is gone,” he said. “What we’re seeing now is people getting retested four, five, six, eight times – and that’s completely unnecessary.”

Giroir also said that it is known that PCR tests can be positive and a person not be infectious. This can keep people out of schools and workplaces unnecessarily.

“It wastes resources, clogs up the system and it’s unnecessary,” Giroir said. “You do not need to be retested if you follow those clinical guidelines.”

The exception is if you’re in the hospital, very sick or immunocompromised, as you can shed the virus for a lot longer and that is a different situation, according to Giroir.

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